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The Period Party Podcast · EP. 71 · November 2, 2020

Science-based Hacks for the Female Brain

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podcast guest

Listen on: Apple Podcasts Spotify

Dr. Sara Gottfried is a board-certified physician scientist and three-time New York Times bestselling author. Dr. Gottfried graduated from Harvard Medical School and the Massachusetts Institute of Technology and completed her residency at the University of California at San Francisco. Over the past three decades, Dr. Gottfried has seen more than 25,000 patients and specializes in identifying the underlying cause of her patients’ conditions to achieve true and lasting health transformations, not just symptom management. She is a wife, mom, researcher, and certified yoga teacher. Her bestselling books include The Hormone Cure, The Hormone Reset Diet, Younger, and her latest, Brain Body Diet.

In this episode, we talk about what you can do to support your brain health as you get older, the impact of diet and lifestyle on mental health, the negative impact of certain sociocultural norms for women, the importance of connecting with other women, and so much more!

Episode Highlights

Fix Your Period

How Fix Your Period Connects Gut Health to Your Hormones

Nicole has long taught that gut health is foundational to hormonal health — the estrobolome, intestinal permeability, and microbiome diversity all directly affect the menstrual cycle. Here's how the app supports this work.

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Symptom Tracking

Track the gut-hormone connection through bloating, mood, energy, cravings, cycle regularity, and skin symptoms — the patterns that signal gut-driven hormonal disruption.

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Hormone Health Assessment

Take Nicole's free Hormone Health Assessment and get personalised results that reveal the symptom clusters most associated with estrogen dominance driven by poor gut health.

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Gut Health Protocols

Fix Your Period Premium includes Nicole's gut health protocols — covering microbiome support, leaky gut repair, SIBO, and the estrobolome's role in estrogen clearance.

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Gut-Hormone Education

Nicole's signature Period Pillars include a dedicated deep-dive on the gut-hormone connection — one of the most overlooked drivers of period problems.

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Nicole.AI

Fix Your Period Premium includes Nicole.AI — trained on Nicole's methodology — giving you personalised answers to your questions about gut health and hormonal balance.

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Personalised Protocol

Fix Your Period Premium unlocks your personalised protocol from your assessment results — a targeted roadmap for addressing gut-driven hormonal imbalances.

Explore the App — It's Free to Start

Frequently Asked Questions

Common questions from this episode — and how Fix Your Period can help.

What is the gut-hormone connection?
The gut microbiome plays a direct role in hormone metabolism. The estrobolome — the collection of gut bacteria that metabolise estrogen — determines how much estrogen gets reabsorbed into circulation vs. excreted. Poor gut health leads to estrogen recirculation, driving estrogen dominance and worsening period symptoms.
How does leaky gut affect hormones?
Intestinal permeability (leaky gut) allows bacterial toxins (LPS) into the bloodstream, triggering systemic inflammation that disrupts hormone signalling, stresses the adrenal glands, and impairs thyroid function. Healing the gut lining is often a foundational step in addressing hormonal imbalances.
What are signs that gut health is affecting my period?
Signs include bloating that worsens before your period, estrogen dominance symptoms (heavy periods, clots, breast tenderness, PMS), irregular cycles, skin issues like hormonal acne, and mood disruption — particularly anxiety and depression around the luteal phase.
Is there an app that addresses the gut-hormone connection?
Yes. Fix Your Period's free assessment identifies gut-linked hormonal patterns. Fix Your Period Premium unlocks Nicole's gut health protocols, dedicated Period Pillars education on the gut-hormone axis, and Nicole.AI for personalised support.
How does nutrition support the gut-hormone axis?
Key strategies include increasing dietary fibre (which binds excess estrogen for excretion), eating fermented foods to diversify the microbiome, reducing inflammatory foods that damage the gut lining, and addressing specific dysbiosis or SIBO with targeted protocols.
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