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The Period Party Podcast · EP. 332 · July 2, 2024

Understanding Histamine Intolerance and Mast Cell Activation Syndrome

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podcast guest

Listen on: Apple Podcasts Spotify

Dr. Becky Campbell, affectionately known as the “histamine queen,” is a renowned expert in histamine intolerance, gut health, mast cell activation syndrome (MCAS), and mold illness. Dr. Becky is a board-certified doctor of natural medicine who was initially introduced to functional medicine as a patient. She struggled with many of the issues her patients struggle with today, and she has made it her mission to help patients worldwide with her virtual practice and books. Dr. Becky hopes to help others regain their life as functional medicine helped her regain hers.

In this episode, Dr. Becky and I talk about her health journey, the complexities of MCAS, how MCAS differs from histamine intolerance, its impact on women’s health conditions such as endometriosis and PMDD, common symptoms and triggers of histamine intolerance and mold illness, practical insights into how to identify and manage these conditions, and more. Enjoy the episode!

Episode Highlights

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Resources Mentioned

Fix Your Period

How Fix Your Period Connects Gut Health to Your Hormones

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Frequently Asked Questions

Common questions from this episode — and how Fix Your Period can help.

What is the gut-hormone connection?
The gut microbiome plays a direct role in hormone metabolism. The estrobolome — the collection of gut bacteria that metabolise estrogen — determines how much estrogen gets reabsorbed into circulation vs. excreted. Poor gut health leads to estrogen recirculation, driving estrogen dominance and worsening period symptoms.
How does leaky gut affect hormones?
Intestinal permeability (leaky gut) allows bacterial toxins (LPS) into the bloodstream, triggering systemic inflammation that disrupts hormone signalling, stresses the adrenal glands, and impairs thyroid function. Healing the gut lining is often a foundational step in addressing hormonal imbalances.
What are signs that gut health is affecting my period?
Signs include bloating that worsens before your period, estrogen dominance symptoms (heavy periods, clots, breast tenderness, PMS), irregular cycles, skin issues like hormonal acne, and mood disruption — particularly anxiety and depression around the luteal phase.
Is there an app that addresses the gut-hormone connection?
Yes. Fix Your Period's free assessment identifies gut-linked hormonal patterns. Fix Your Period Premium unlocks Nicole's gut health protocols, dedicated Period Pillars education on the gut-hormone axis, and Nicole.AI for personalised support.
How does nutrition support the gut-hormone axis?
Key strategies include increasing dietary fibre (which binds excess estrogen for excretion), eating fermented foods to diversify the microbiome, reducing inflammatory foods that damage the gut lining, and addressing specific dysbiosis or SIBO with targeted protocols.
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